Opko Health Stock Analysis

OPK Stock  USD 1.23  0.02  1.65%   
Below is the normalized historical share price chart for Opko Health extending back to November 02, 1995. This chart has been adjusted for all splits and dividends and is plotted against all major global economic recessions. As of today, the current price of Opko Health stands at 1.23, as last reported on the 16th of February 2026, with the highest price reaching 1.27 and the lowest price hitting 1.21 during the day.
IPO Date
2nd of November 1995
200 Day MA
1.3551
50 Day MA
1.3036
Beta
1.493
 
Dot-com Bubble
 
Housing Crash
 
Credit Downgrade
 
Yuan Drop
 
Covid
 
Interest Hikes
Opko Health holds a debt-to-equity ratio of 0.164. At this time, Opko Health's Debt To Assets are quite stable compared to the past year. Debt Ratio is expected to rise to 0.22 this year, although the value of Net Debt To EBITDA will most likely fall to 0.59. Opko Health's financial risk is the risk to Opko Health stockholders that is caused by an increase in debt.

Asset vs Debt

Equity vs Debt

Opko Health's liquidity is one of the most fundamental aspects of both its future profitability and its ability to meet different types of ongoing financial obligations. Opko Health's cash, liquid assets, total liabilities, and shareholder equity can be utilized to evaluate how much leverage the Company is using to sustain its current operations. For traders, higher-leverage indicators usually imply a higher risk to shareholders. In addition, it helps Opko Stock's retail investors understand whether an upcoming fall or rise in the market will negatively affect Opko Health's stakeholders.
For many companies, including Opko Health, marketable securities, inventories, and receivables are the most common assets that could be converted to cash. However, for Opko Health, the most critical issue when managing liquidity is ensuring that current assets are properly aligned with current liabilities. If they are not, Opko Health's management will need to obtain alternative financing to ensure there are always enough cash equivalents on the balance sheet to meet obligations.
Price Book
0.7233
Enterprise Value Ebitda
20.4507
Price Sales
1.5206
Shares Float
348 M
Wall Street Target Price
3.5583
At this time, Opko Health's Common Stock is quite stable compared to the past year. Stock Based Compensation is expected to rise to about 15 M this year, although the value of Preferred Stock And Other Adjustments will most likely fall to about 359.1 K. . The value of Price To Sales Ratio is estimated to slide to 1.56. The value of Price Earnings Ratio is estimated to slide to -23.15.
Opko Health is undervalued with Real Value of 1.82 and Target Price of 3.56. The main objective of Opko Health stock analysis is to determine its intrinsic value, which is an estimate of what Opko Health is worth, separate from its market price. There are two main types of Opko Health's stock analysis: fundamental analysis and technical analysis.
The Opko Health stock is traded in the USA on NASDAQ Exchange, with the market opening at 09:30:00 and closing at 16:00:00 every Mon,Tue,Wed,Thu,Fri except for officially observed holidays in the USA.
Check out Your Equity Center to better understand how to build diversified portfolios, which includes a position in Opko Health. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in employment.
For more information on how to buy Opko Stock please use our How to buy in Opko Stock guide.

Opko Stock Analysis Notes

About 49.0% of the company outstanding shares are owned by corporate insiders. The company has price-to-book ratio of 0.72. Typically companies with comparable Price to Book (P/B) are able to outperform the market in the long run. Opko Health recorded a loss per share of 0.24. The entity had not issued any dividends in recent years. OPKO Health, Inc., a healthcare company, engages in the diagnostics and pharmaceuticals businesses in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company was founded in 1991 and is headquartered in Miami, Florida. Opko Health operates under Diagnostics Research classification in the United States and is traded on NASDAQ Exchange. It employs 5767 people. To find out more about Opko Health contact Phillip Frost at 305 575 4100 or learn more at https://www.opko.com.

Opko Health Investment Alerts

Opko Health generated a negative expected return over the last 90 days
Opko Health may become a speculative penny stock
The company reported the last year's revenue of 713.14 M. Reported Net Loss for the year was (53.22 M) with profit before taxes, overhead, and interest of 121.55 M.
Opko Health has about 210.46 M in cash with (183.49 M) of positive cash flow from operations. This results in cash-per-share (CPS) ratio of 0.27.
Opko Health has a very weak financial position based on the latest SEC disclosures
Roughly 49.0% of the company outstanding shares are owned by corporate insiders
Latest headline from globenewswire.com: OPKO Health to Report Fourth Quarter 2025 Financial Results on February 26

Opko Largest EPS Surprises

Earnings surprises can significantly impact Opko Health's stock price both in the short term and over time. Negative earnings surprises usually result in a price decline. However, it has been seen that positive earnings surprises lead to an immediate rise in a stock's price and a gradual increase over time. This is why we often hear news about some companies beating earning projections. Financial analysts spend a large amount of time predicting earnings per share (EPS) along with other important future indicators. Many analysts use forecasting models, management guidance, and additional fundamental information to derive an EPS estimate.
Reported
Fiscal Date
Estimated EPS
Reported EPS
Surprise
2016-02-29
2015-12-310.00170.00290.001270 
2023-11-06
2023-09-30-0.1-0.11-0.0110 
2021-02-18
2020-12-310.040.050.0125 
View All Earnings Estimates

Opko Stock Institutional Investors

Institutional investors include commercial and private banks, credit unions, insurance companies, pension funds, hedge funds, endowments, and mutual funds. Operating companies that invest excess capital in these types of assets may also be included in the term and may influence corporate governance by exercising voting rights in their investments.
Shares
Morgan Stanley - Brokerage Accounts2025-06-30
2.1 M
Awm Investment Company Inc2025-06-30
M
Dimensional Fund Advisors, Inc.2025-06-30
1.9 M
Graham Capital Management2025-06-30
1.9 M
Bank Of America Corp2025-06-30
1.9 M
Two Sigma Investments Llc2025-06-30
1.8 M
Whitefort Capital Management, Lp.2025-06-30
1.8 M
Y.d. More Investments Ltd2025-06-30
1.5 M
Jane Street Group Llc2025-06-30
1.4 M
Rubric Capital Management Lp2025-06-30
47.8 M
Vanguard Group Inc2025-06-30
38.2 M
Note, although Opko Health's institutional investors appear to be way more sophisticated than retail investors, it remains unclear if professional active investment managers can reliably enhance risk-adjusted returns by an amount that exceeds fees and expenses.

Opko Market Capitalization

The company currently falls under 'Small-Cap' category with a total capitalization of 976.35 M.

Opko Profitablity

The company has Net Profit Margin of (0.28) %, which means that it does not effectively control expenditures or properly executes on its pricing strategies. This is way below average. In the same way, it shows Net Operating Margin of (0.35) %, which entails that for every $100 of revenue, it lost $0.35.
Last ReportedProjected for Next Year
Return On Tangible Assets(0.06)(0.06)
Return On Capital Employed(0.07)(0.07)
Return On Assets(0.02)(0.02)
Return On Equity(0.04)(0.04)

Management Efficiency

Opko Health has Return on Asset of (0.0615) % which means that on every $100 spent on assets, it lost $0.0615. This is way below average. In the same way, it shows a return on shareholders' equity (ROE) of (0.1332) %, meaning that it generated no profit with money invested by stockholders. Opko Health's management efficiency ratios could be used to measure how well Opko Health manages its routine affairs as well as how well it operates its assets and liabilities. The value of Return On Tangible Assets is estimated to slide to -0.06. The value of Return On Capital Employed is expected to slide to -0.07. At this time, Opko Health's Total Current Liabilities is quite stable compared to the past year. Liabilities And Stockholders Equity is expected to rise to about 2.7 B this year, although the value of Non Current Liabilities Other will most likely fall to about 9.8 M.
Last ReportedProjected for Next Year
Book Value Per Share 1.77  1.18 
Tangible Book Value Per Share 0.04  0.04 
Enterprise Value Over EBITDA 7.27  4.41 
Price Book Value Ratio 0.86  0.82 
Enterprise Value Multiple 7.27  4.41 
Price Fair Value 0.86  0.82 
Enterprise Value2.9 B1.9 B
Effective leadership at Opko Health drives its competitive edge in the market. Our analysis focuses on how this translates to financial performance and stock value.
Operating Margin
(0.35)
Profit Margin
(0.28)
Beta
1.493
Return On Assets
(0.06)
Return On Equity
(0.13)

Technical Drivers

As of the 16th of February 2026, Opko Health holds the Risk Adjusted Performance of (0.04), coefficient of variation of (1,897), and Variance of 3.64. Compared to fundamental indicators, the technical analysis model allows you to check existing technical drivers of Opko Health, as well as the relationship between them.

Opko Health Price Movement Analysis

Execute Study
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Opko Health Insider Trading Activities

Some recent studies suggest that insider trading raises the cost of capital for securities issuers and decreases overall economic growth. Trading by specific Opko Health insiders, such as employees or executives, is commonly permitted as long as it does not rely on Opko Health's material information that is not in the public domain. Local jurisdictions usually require such trading to be reported in order to monitor insider transactions. In many U.S. states, trading conducted by corporate officers, key employees, directors, or significant shareholders must be reported to the regulator or publicly disclosed, usually within a few business days of the trade. In these cases Opko Health insiders are required to file a Form 4 with the U.S. Securities and Exchange Commission (SEC) when buying or selling shares of their own companies.

Opko Health Outstanding Bonds

Opko Health issues bonds to finance its operations. Corporate bonds make up one of the largest components of the U.S. bond market, which is considered the world's largest securities market. Opko Health uses the proceeds from bond sales for a wide variety of purposes, including financing ongoing mergers and acquisitions, buying new equipment, investing in research and development, buying back their own stock, paying dividends to shareholders, and even refinancing existing debt. Most Opko bonds can be classified according to their maturity, which is the date when Opko Health has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Opko Health Predictive Daily Indicators

Opko Health intraday indicators are useful technical analysis tools used by many experienced traders. Just like the conventional technical analysis, daily indicators help intraday investors to analyze the price movement with the timing of Opko Health stock daily movement. By combining multiple daily indicators into a single trading strategy, you can limit your risk while still earning strong returns on your managed positions.

Opko Health Forecast Models

Opko Health's time-series forecasting models are one of many Opko Health's stock analysis techniques aimed at predicting future share value based on previously observed values. Time-series forecasting models ae widely used for non-stationary data. Non-stationary data are called the data whose statistical properties e.g. the mean and standard deviation are not constant over time but instead, these metrics vary over time. These non-stationary Opko Health's historical data is usually called time-series. Some empirical experimentation suggests that the statistical forecasting models outperform the models based exclusively on fundamental analysis to predict the direction of the market movement and maximize returns from investment trading.

Opko Health Bond Ratings

Opko Health financial ratings play a critical role in determining how much Opko Health have to pay to access credit markets, i.e., the amount of interest on their issued debt. The threshold between investment-grade and speculative-grade ratings has important market implications for Opko Health's borrowing costs.
Piotroski F Score
1
Very WeakView
Beneish M Score
(2.71)
Unlikely ManipulatorView

Opko Health Debt to Cash Allocation

Opko Health has 504.44 M in debt with debt to equity (D/E) ratio of 0.16, which may show that the company is not taking advantage of profits from borrowing. Opko Health has a current ratio of 2.25, demonstrating that it is liquid and is capable to disburse its financial commitments when the payables are due. That said, strategic use of leverage may enable Opko to fund expansion initiatives and generate superior returns.

Opko Health Total Assets Over Time

Opko Health Assets Financed by Debt

The debt-to-assets ratio shows the degree to which Opko Health uses debt to finance its assets. It includes both long-term and short-term borrowings maturing within one year. It also includes both tangible and intangible assets, such as goodwill.

Opko Health Debt Ratio

    
  22.0   
It seems most of the Opko Health's assets are financed through equity. Typically, companies with high debt-to-asset ratios are said to be highly leveraged. The higher the ratio, the greater risk will be associated with the Opko Health's operation. In addition, a high debt-to-assets ratio may indicate a low borrowing capacity of Opko Health, which in turn will lower the firm's financial flexibility.

Opko Health Corporate Bonds Issued

Opko Net Debt

Net Debt

87.55 Million

At this time, Opko Health's Net Debt is quite stable compared to the past year.

About Opko Stock Analysis

Stock analysis is the technique used by a trader or investor to examine and evaluate how Opko Health prices is reacting to, or reflecting on a current market direction and economic conditions. It can be used to make informed decisions about market timing, and when buying or selling Opko shares will generate the highest return on investment. We also built our stock analysis module to help investors to gain an insight into the world economy as a whole, the stock market, thematic ideas. a specific sector, or an individual Stock such as Opko Health. By using and applying Opko Stock analysis, traders can create a robust methodology for identifying Opko entry and exit points for their positions.
Last ReportedProjected for Next Year
Pretax Profit Margin(0.01)(0.01)
Operating Profit Margin(0.19)(0.20)
Net Loss(0.07)(0.07)
Gross Profit Margin 0.50  0.54 

Current Opko Analysis - Recommendations

We track the performance of the top 100 financial experts across various large and mid-size financial boutiques. Opko analyst recommendations are determined by taking all analyst recommendations and averaging them as Strong Buy, Buy, Hold, Strong Sell or Sell. There is no one specific way to measure analysis performance other than comparing it to the past results via a very sophisticated attribution analysis. Opko analyst consensus and target price projections should be used in combination with other traditional techniques such as stock price forecasting, technical analysis, earnings estimate, and various momentum models.
Target PriceConsensus# of Analysts
3.56Strong Buy7Odds
Opko Health current and past analyst recommendations published by a number of research institutions as well as average analyst consensus.
Most Opko analysts issue ratings four times a year, at intervals of three months. Ratings are usually accompanied by a target price to helps potential investors understand Opko stock's fair price compared to its market value. Analysts arrive at stock ratings after researching public financial statements of Opko Health, talking to its executives and customers, or listening to Opko conference calls.
Opko Analyst Advice Details

Opko Stock Analysis Indicators

Opko Health stock analysis indicators help investors evaluate how Opko Health stock reacts to ongoing and evolving market conditions. The investors can use it to make informed decisions about market timing and determine when trading Opko Health shares will generate the highest return on investment. By understating and applying Opko Health stock analysis, traders can identify Opko Health position entry and exit signals to maximize returns.
Begin Period Cash Flow95.9 M
Long Term Debt422.2 M
Common Stock Shares Outstanding694 M
Total Stockholder Equity1.4 B
Total Cashflows From Investing Activities352.2 M
Tax Provision42.8 M
Quarterly Earnings Growth Y O Y-0.126
Property Plant And Equipment Net124.1 M
Cash And Short Term Investments431.9 M
Cash431.9 M
Accounts Payable47.1 M
Net Debt72.5 M
50 Day M A1.3036
Total Current Liabilities193.1 M
Other Operating Expenses865.2 M
Non Current Assets Total1.5 B
Forward Price Earnings64.5161
Non Currrent Assets Other18.5 M
Stock Based Compensation11 M
When determining whether Opko Health is a good investment, qualitative aspects like company management, corporate governance, and ethical practices play a significant role. A comparison with peer companies also provides context and helps to understand if Opko Stock is undervalued or overvalued. This multi-faceted approach, blending both quantitative and qualitative analysis, forms a solid foundation for making an informed investment decision about Opko Health Stock. Highlighted below are key reports to facilitate an investment decision about Opko Health Stock:
Check out Your Equity Center to better understand how to build diversified portfolios, which includes a position in Opko Health. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in employment.
For more information on how to buy Opko Stock please use our How to buy in Opko Stock guide.
You can also try the Efficient Frontier module to plot and analyze your portfolio and positions against risk-return landscape of the market..
Is Biotechnology space expected to grow? Or is there an opportunity to expand the business' product line in the future? Factors like these will boost the valuation of Opko Health. Anticipated expansion of Opko directly elevates investor willingness to pay premium valuations. The financial industry is built on trying to define current growth potential and future valuation accurately. Comprehensive Opko Health assessment requires weighing all these inputs, though not all factors influence outcomes equally.
Quarterly Earnings Growth
(0.13)
Earnings Share
(0.24)
Revenue Per Share
0.881
Return On Assets
(0.06)
Return On Equity
(0.13)
The market value of Opko Health is measured differently than its book value, which is the value of Opko that is recorded on the company's balance sheet. Investors also form their own opinion of Opko Health's value that differs from its market value or its book value, called intrinsic value, which is Opko Health's true underlying value. Investors use various methods to calculate intrinsic value and buy a stock when its market value falls below its intrinsic value. Because Opko Health's market value can be influenced by many factors that don't directly affect Opko Health's underlying business (such as a pandemic or basic market pessimism), market value can vary widely from intrinsic value.
It's important to distinguish between Opko Health's intrinsic value and market price, which are calculated using different methodologies. Investment decisions regarding Opko Health should consider multiple factors including financial performance, growth metrics, competitive position, and professional analysis. Meanwhile, Opko Health's quoted price indicates the marketplace figure where supply meets demand through bilateral consent.